Physical activity pre- and post-dementia: English Longitudinal Study of Ageing

Soni, Mira, Orrell, Martin, Bandelow, Stephan, Steptoe, Andrew, Rafnsson, Snorri, d'Orsi, Eleonora, Xavier, Andre and Hogervorst, Eef (2017) Physical activity pre- and post-dementia: English Longitudinal Study of Ageing. Aging and Mental Health . ISSN 1364-6915

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Background: To inform public health interventions, further investigation is needed to identify: (1) frequency/intensity of everyday physical activity (PA) needed to reduce dementia risk; (2) whether post-diagnosis reduction in PA is associated with cognitive outcomes. Methods: Data from 11,391 men and women (aged ≥50) were obtained in the English Longitudinal Study of Ageing. Assessments were at baseline (2002-2003) and biannual follow-ups (2004-2013).

Results: Older adults who carried out moderate to vigorous activity at least once per week had a 34%-50% lower risk for cognitive decline and dementia over an 8-10 year follow-up period. From pre- to post-diagnosis, those that decreased PA levels had a larger decrease in immediate recall score, compared to those that maintained or increased PA levels (adjusted for changes in physical function).

Conclusion: These findings provide a guideline for everyday PA levels needed to reduce risk for dementia. Reduction in PA after diagnosis was also associated with accelerated cognitive decline.

Item Type: Article
Keywords: Alzheimer’s Disease, Other Dementias, Epidemiology (Dementia), Physical Activity, Cognitive Functioning
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Psychiatry and Applied Psychology
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Depositing User: Eprints, Support
Date Deposited: 02 Mar 2018 13:13
Last Modified: 04 May 2020 19:12

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