Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy.

Ghita, Adrian and Pascut, Flavius C. and Sottile, Virginie and Notingher, Ioan (2013) Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy. Analyst, 139 (1). pp. 55-58. ISSN 1364-5528

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Abstract

Raman microscopy was used as a label-free method to study the mineralisation of bone nodules formed by mesenchymal stem cells cultured in osteogenic medium in vitro. Monitoring individual bone nodules over 28 days revealed temporal and spatial changes in the crystalline phase of the hydroxyapatite components of the nodules.

Item Type: Article
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Cancer and Stem Cells
University of Nottingham, UK > Faculty of Science > School of Physics and Astronomy
Identification Number: https://doi.org/10.1039/C3AN01716H
Depositing User: Sottile, Virginie
Date Deposited: 21 Feb 2018 15:22
Last Modified: 21 Feb 2018 15:22
URI: http://eprints.nottingham.ac.uk/id/eprint/49915

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