Synthesis and characterisation of multi-substituted hydroxyapatites

McCarthy, Benjamin P. (2018) Synthesis and characterisation of multi-substituted hydroxyapatites. PhD thesis, University of Nottingham.

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Abstract

This thesis presents a range of novel mono and di-substituted hydroxyapatite powders, characterised by a range of techniques to ascertain their chemical composition, crystallographic composition, physical properties, and in vitro bioactivity.

The novel compositions consist of substituting a range of Borate, Sulphate, Silicate, and Strontium in levels ranging from 1.5 mol.%, up to 5 mol.%. It was found that a 4 mol.% inclusion of 2 mol.% Sr2+ and 2 mol.% SO42- gave a significant increase in the amount of osteocalcin produced and may represent an improved biomaterial warranting further study.

Item Type: Thesis (University of Nottingham only) (PhD)
Supervisors: Grant, David
Scotchford, Colin A.
Jackson, Philip
Keywords: Hydroxyapatite; Implants, Artificial
Subjects: R Medicine > RD Surgery
Faculties/Schools: UK Campuses > Faculty of Engineering
Item ID: 47482
Depositing User: McCarthy, Ben
Date Deposited: 13 Jul 2018 04:40
Last Modified: 08 May 2020 08:33
URI: http://eprints.nottingham.ac.uk/id/eprint/47482

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