Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle

Furse, Samuel and Jakubec, Martin and Rise, Frode and Williams, Huw E.L. and Rees, Catherine and Halskau, Øyvind (2017) Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle. Scientific Reports, 7 . 8012/1-8012/11. ISSN 2045-2322

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Abstract

This paper reports that the abundances of endogenous cardiolipin and phosphatidylethanolamine halve during elongation of the Gram-positive bacterium Listeria innocua. The lyotropic phase behaviour of model lipid systems that describe these modulations in lipid composition indicate that the average stored curvature elastic stress of the membrane is reduced on elongation of the cell, while the fluidity appears to be maintained. These findings suggest that phospholipid metabolism is linked to the cell cycle and that changes in membrane composition can lower the energetic barrier to the succeeding stage of the cell cycle. This therefore suggests a means by which bacteria can manage the physical properties of their membranes through the cell cycle.

Item Type: Article
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Biosciences > Division of Food Sciences
Identification Number: 10.1038/s41598-017-06855-z
Depositing User: Rees, Cath
Date Deposited: 01 Sep 2017 08:31
Last Modified: 18 Oct 2017 17:54
URI: http://eprints.nottingham.ac.uk/id/eprint/45345

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