Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy

Franchi, Martino V. and Longo, Stefano and Mallinson, Joanne E. and Quinlan, Jonathan I. and Taylor, Tariq and Greenhaff, Paul L. and Narici, Marco V. (2017) Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy. Scandinavian Journal of Medicine & Science in Sports . ISSN 1600-0838 (In Press)

[img] PDF - Repository staff only until 14 August 2018. - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Download (644kB)

Abstract

Aim: Muscle thickness (MT) measured by ultrasound has been used to estimate cross-sectional area (measured by CT and MRI) at a single time-point. We tested whether MT could be used as a valid marker of MRI determined muscle anatomical cross-sectional area (ACSA) and volume changes following resistance training (RT).

Methods: Nine healthy, young, male volunteers (24±2 y.o., BMI 24.1±2.8 kg/m2) had vastus lateralis (VL) muscle volume (VOL) and ACSA mid (at 50% of femur length, FL) assessed by MRI, and VL MT measured by ultrasound at 50% FL. Measurements were taken at baseline and after 12 weeks of isokinetic RT. Differences between baseline and post-training were assessed by Student’s paired t-test. The relationships between MRI and ultrasound measurements were tested by Pearson’s correlation.

Results: After RT, MT increased by 7.5±6.1% (p<0.001), ACSAmid by 5.2±5% (p<0.001) and VOL by 5.0±6.9% (p<0.05) (values: means±S.D.). Positive correlations were found, at baseline and 12 weeks, between MT and ACSAmid (r=0.82, p<0.001 and r=0.73, p<0.001, respectively), and between MT and VOL (r=0.76, p < 0.001 and r=0.73, p < 0.001, respectively). The % change in MT with training was correlated with % change in ACSAmid (r=0.69, p = 0.01), but not % change in VOL (r= 0.33, p>0.05).

Conclusions: These data support evidence that MT is a reliable index of muscle ACSAmid and VOL at a single time-point. MT changes following RT are associated with parallel changes in muscle ACSAmid but not with the changes in VOL, highlighting the impact of RT on regional hypertrophy.

Item Type: Article
Keywords: MRI ; ACSA ; Ultrasound; Volume
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine
University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Life Sciences
Identification Number: 10.1111/sms.12961
Depositing User: Eprints, Support
Date Deposited: 24 Aug 2017 13:43
Last Modified: 24 Aug 2017 21:08
URI: http://eprints.nottingham.ac.uk/id/eprint/45129

Actions (Archive Staff Only)

Edit View Edit View