A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trialTools Harrison, Eleanor F. and Haines, Rachel H. and Cowdell, Fiona and Sach, Tracey H. and Dean, Taraneh and Pollock, Ian and Burrows, Nigel P. and Buckley, Hannah and Batchelor, Jonathan M. and Williams, Hywel C. and Lawton, Sandra and Brown, Sara J. and Bradshaw, Lucy E. and Ahmed, Amina and Montgomery, Alan A. and Mitchell, Eleanor and Thomas, Kim S. (2015) A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial. Trials, 16 . p. 390. ISSN 1745-6215 Full text not available from this repository.AbstractBackground: Eczema is a chronic, itchy skin condition that can have a large impact on the quality of life of patients and their families. People with eczema are often keen to try out non-pharmacological therapies like silk therapeutic garments that could reduce itching or the damage caused by scratching. However, the effectiveness and cost-effectiveness of these garments in the management of eczema has yet to be proven. The CLOTHES Trial will test the hypothesis that ‘silk therapeutic garments plus standard eczema care’ is superior to ‘standard care alone’ for children with moderate to severe eczema.
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