NMR hyperpolarization techniques of gases

Barskiy, Danila A. and Coffey, Aaron M. and Nikolaou, Panayiotis and Mikhaylov, Dmitry M. and Goodson, Boyd M. and Branca, Rosa T. and Lu, George J. and Shapiro, Mikhail G. and Telkki, Ville-Veikko and Zhivonitko, Vladimir V. and Koptyug, Igor V. and Salnikov, Oleg G. and Kovtunov, Kirill V. and Bukhtiyarov, Valerii I. and Rosen, Matthew S. and Barlow, Michael J. and Safavi, Shahideh and Hall, Ian P. and Schröder, Leif and Chekmenev, Eduard Y. (2017) NMR hyperpolarization techniques of gases. Chemistry - a European Journal, 23 (4). pp. 725-751. ISSN 0947-6539

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Abstract

Nuclear spin polarization can be significantly increased through the process of hyperpolarization, leading to an increase in the sensitivity of nuclear magnetic resonance (NMR) experiments by 4–8 orders of magnitude. Hyperpolarized gases, unlike liquids and solids, can often be readily separated and purified from the compounds used to mediate the hyperpolarization processes. These pure hyperpolarized gases enabled many novel MRI applications including the visualization of void spaces, imaging of lung function, and remote detection. Additionally, hyperpolarized gases can be dissolved in liquids and can be used as sensitive molecular probes and reporters. This Minireview covers the fundamentals of the preparation of hyperpolarized gases and focuses on selected applications of interest to biomedicine and materials science.

Item Type: Article
Additional Information: This is the peer reviewed version of the following article: D. A. Barskiy, A. M. Coffey, P. Nikolaou, D. M. Mikhaylov, B. M. Goodson, R. T. Branca, G. J. Lu, M. G. Shapiro, V.-V. Telkki, V. V. Zhivonitko, I. V. Koptyug, O. G. Salnikov, K. V. Kovtunov, V. I. Bukhtiyarov, M. S. Rosen, M. J. Barlow, S. Safavi, I. P. Hall, L. Schröder, E. Y. Chekmenev, Chem. Eur. J. 2017, 23, 725., which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/chem.201603884/abstract. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Respiratory Medicine
Identification Number: 10.1002/chem.201603884
Depositing User: Eprints, Support
Date Deposited: 21 Jul 2017 10:08
Last Modified: 21 Jul 2017 21:59
URI: http://eprints.nottingham.ac.uk/id/eprint/44361

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