High-resolution self-gated dynamic abdominal MRI using manifold alignment

Chen, Xin and Usman, Muhammad and Baumgartner, Christian F. and Balfour, Daniel R. and Marsden, Paul K. and Reader, Andrew J. and Prieto, Claudia and King, Andrew P. (2017) High-resolution self-gated dynamic abdominal MRI using manifold alignment. IEEE Transactions on Medical Imaging, 36 (4). pp. 960-971. ISSN 1558-254X

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Abstract

We present a novel retrospective self-gating method based on manifold alignment (MA), which enables reconstruction of free-breathing, high spatial and temporal resolution abdominal MRI sequences. Based on a radial golden-angle (RGA) acquisition trajectory, our method enables a multi-dimensional self-gating signal to be extracted from the k-space data for more accurate motion representation. The k-space radial profiles are evenly divided into a number of overlapping groups based on their radial angles. MA is then used to simultaneously learn and align the low dimensional manifolds of all groups, and embed them into a common manifold. In the manifold, k-space profiles that represent similar respiratory positions are close to each other. Image reconstruction is performed by combining radial profiles with evenly distributed angles that are close in the manifold. Our method was evaluated on both 2D and 3D synthetic and in vivo datasets. On the synthetic datasets, our method achieved high correlation with the ground truth in terms of image intensity and virtual navigator values. Using the in vivo data, compared to a state-of-the-art approach based on centre of k-space gating, our method was able to make use of much richer profile data for self-gating, resulting in statistically significantly better quantitative measurements in terms of organ sharpness and image gradient entropy.

Item Type: Article
Keywords: Magnetic resonance imaging (MRI), Reconstruction, Manifold alignment (MA), MRI self-gating, Respiratory motion
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Computer Science
Identification Number: 10.1109/TMI.2016.2636449
Depositing User: Chen, Xin
Date Deposited: 21 Apr 2017 13:44
Last Modified: 21 Apr 2017 13:49
URI: http://eprints.nottingham.ac.uk/id/eprint/41803

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