A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic

Gillis, Richard B. and Adams, Gary G. and Alzahrani, Qushmua and Harding, Stephen E. and Allen Bush, C. (2016) A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic. Biopolymers, 105 (9). pp. 618-625. ISSN 1097-0282

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Abstract

Under investigation are the structural properties of gum arabic, an industrially important biopolymer for use as a stabilizer or in drug delivery, using Analytical Ultracentrifugation—a well-established, matrix-free probe for macromolecular size and shape. These results are combined with chromatographically-coupled methods (multi-angle light scattering, differential press imbalance viscometry) to provide a global analysis of its structure in varying ionic strength conditions. This analysis indicates that gum Arabic may have a compact, elliptical structure in solution, the significance of which for biotechnological use is indicated. This modelling method can be applied to other biopolymers and synthetic polymers.

Item Type: Article
Additional Information: This is the peer reviewed version of the following article: Gillis, R. B., Adams, G. G., Alzahrani, Q. and Harding, S. E. (2016), A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic. Biopolymers, 105: 618–625, which has been published in final form at http://dx.doi.org/10.1002/bip.22823. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Keywords: acacia; AUC; characterization; conformation; gum arabic; hydrodynamic; sedimentation velocity; ultracentrifugation
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Biosciences
Identification Number: 10.1002/bip.22823
Depositing User: Eprints, Support
Date Deposited: 03 Apr 2017 10:12
Last Modified: 13 Oct 2017 01:14
URI: http://eprints.nottingham.ac.uk/id/eprint/41700

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