Genomic insights into cardiomyopathies: a comparative cross-species review

Simpson, Siobhan and Rutland, Paul and Rutland, Catrin S. (2017) Genomic insights into cardiomyopathies: a comparative cross-species review. Veterinary Sciences, 4 (1). 19/1-19/26. ISSN 2306-7381

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Abstract

n the global human population, the leading cause of non-communicable death is cardiovascular disease. It is predicted that by 2030, deaths attributable to cardiovascular disease will have risen to over 20 million per year. This review compares the cardiomyopathies in both human and non-human animals and identifies the genetic associations for each disorder in each species/taxonomic group. Despite differences between species, advances in human medicine can be gained by utilising animal models of cardiac disease; likewise, gains can be made in animal medicine from human genomic insights. Advances could include undertaking regular clinical checks in individuals susceptible to cardiomyopathy, genetic testing prior to breeding, and careful administration of breeding programmes (in non-human animals), further development of treatment regimes, and drugs and diagnostic techniques

Item Type: Article
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Veterinary Medicine and Science
Identification Number: 10.3390/vetsci4010019
Depositing User: Eprints, Support
Date Deposited: 22 Mar 2017 11:45
Last Modified: 19 Apr 2017 13:51
URI: http://eprints.nottingham.ac.uk/id/eprint/41474

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