Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD)

Groom, Madeleine J. and Kochhar, Puja and Hamilton, Antonia and Liddle, Elizabeth B. and Simeou, Marina and Hollis, Chris (2017) Atypical processing of gaze cues and faces explains comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). Journal of Autism and Developmental Disorders, 47 (5). pp. 1496-1509. ISSN 1573-3432

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Abstract

This study investigated the neurobiological basis of comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). We compared children with ASD, ADHD or ADHD+ASD and typically developing controls (CTRL) on behavioural and electrophysiological correlates of gaze cue and face processing. We measured effects of ASD, ADHD and their interaction on the EDAN, an ERP marker of orienting visual attention towards a spatially cued location and the N170, a right-hemisphere lateralised ERP linked to face processing. We identified atypical gaze cue and face processing in children with ASD and ADHD+ASD compared with the ADHD and CTRL groups. The findings indicate a neurobiological basis for the presence of comorbid ASD symptoms in ADHD. Further research using larger samples is needed.

Item Type: Article
Keywords: ASD; ADHD; ERPs; Comorbidity; Gaze cueing; Face processing
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Psychiatry and Applied Psychology
University of Nottingham, UK > Faculty of Science > School of Psychology
Identification Number: 10.1007/s10803-017-3078-4
Depositing User: Eprints, Support
Date Deposited: 10 Mar 2017 10:44
Last Modified: 16 May 2017 10:43
URI: http://eprints.nottingham.ac.uk/id/eprint/41229

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