What influences healthcare professionals' treatment preferences for older women with operable breast cancer?: an application of the discrete choice experiment

Morgan, J.L. and Walters, S.J. and Collins, K. and Robinson, T.G. and Cheung, K.-L. and Audisio, R. and Reed, M.W. and Wyld, L. (2017) What influences healthcare professionals' treatment preferences for older women with operable breast cancer?: an application of the discrete choice experiment. European Journal of Surgical Oncology (EJSO) . ISSN 0748-7983 (In Press)

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Abstract

Introduction

Primary endocrine therapy (PET) is used variably in the UK as an alternative to surgery for older women with operable breast cancer. Guidelines state that only patients with “significant comorbidity” or “reduced life expectancy” should be treated this way and age should not be a factor.

Methods

A Discrete Choice Experiment (DCE) was used to determine the impact of key variables (patient age, comorbidity, cognition, functional status, cancer stage, cancer biology) on healthcare professionals' (HCP) treatment preferences for operable breast cancer among older women. Multinomial logistic regression was used to identify associations.

Results

40% (258/641) of questionnaires were returned. Five variables (age, co-morbidity, cognition, functional status and cancer size) independently demonstrated a significant association with treatment preference (p < 0.05). Functional status was omitted from the multivariable model due to collinearity, with all other variables correlating with a preference for operative treatment over no preference (p < 0.05). Only co-morbidity, cognition and cancer size correlated with a preference for PET over no preference (p < 0.05).

Conclusion

The majority of respondents selected treatment in accordance with current guidelines, however in some scenarios, opinion was divided, and age did appear to be an independent factor that HCPs considered when making a treatment decision in this population.

Item Type: Article
Keywords: Breast cancer; Primary endocrine therapy; Surgery; Discrete choice experiment; Older
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine
Identification Number: 10.1016/j.ejso.2017.01.012
Depositing User: Eprints, Support
Date Deposited: 01 Mar 2017 11:58
Last Modified: 20 Mar 2017 06:48
URI: http://eprints.nottingham.ac.uk/id/eprint/40947

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