Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata

Planchestainer, Matteo and Contente, Martina Letizia and Cassidy, Jennifer and Molinari, Francesco and Tamborini, Lucia and Paradisi, Francesca (2017) Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata. Green Chemistry, 19 . pp. 372-375. ISSN 1463-9262

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Abstract

The continuous flow synthesis of a series of amines was successfully achieved by exploiting the enhanced stability and broad substrate scope of an immobilised transaminases from Halomonas elongata (HEWT). A series of substrates were tested in flow reactors and transformed to the corresponding amines in good to excellent yields. The process was implemented with an integrated in-line purification step for the recovery of the pure amines.

Item Type: Article
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Chemistry
Identification Number: 10.1039/c6gc01780k
Depositing User: Bramwell, Roseanna
Date Deposited: 27 Jan 2017 11:34
Last Modified: 03 Aug 2017 04:30
URI: http://eprints.nottingham.ac.uk/id/eprint/40105

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