Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes

Rawson, Frankie J. and Cole, M.T and Hicks, Jacqueline and Aylott, Jonathan W. and Milne, W.I. and Collins, C.M. and Jackson, Simon K. and Silman, Nigel and Mendes, Paula M. (2016) Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes. Scientific Reports, 6 (37672). ISSN 2045-2322

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Abstract

With the rapidly increasing demands for ultrasensitive biodetection, the design and applications of new nano-scale materials for development of sensors based on optical and electrochemical transducers have attracted substantial interest. In particular, given the comparable sizes of nanomaterials and biomolecules, there exist plenty of opportunities to develop functional nanoprobes with biomolecules for highly sensitive and selective biosensing, shedding new light on cellular behaviour. Towards this aim, herein we interface cells with patterned nano-arrays of carbon nanofibers forming a nanosensor-cell construct. We show that such a construct is capable of electrochemically communicating with the intracellular environment.

Item Type: Article
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Pharmacy
Identification Number: 10.1038/srep37672
Depositing User: Eprints, Support
Date Deposited: 13 Jan 2017 08:56
Last Modified: 01 Jul 2017 03:35
URI: http://eprints.nottingham.ac.uk/id/eprint/39832

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