Detection of a Yersinia pestisgene homologue in rodent samples

Giles, Timothy A. and Greenwood, Alex D. and Tsangaras, Kyriakos and Giles, Tom C. and Barrow, Paul A. and Hannant, Duncan and Abu-Median, Abu-Bakr and Yon, Lisa (2016) Detection of a Yersinia pestisgene homologue in rodent samples. PeerJ, 4 . e2216/1-e2216/9. ISSN 2167-8359

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Abstract

A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. Samples were from urban locations in the UK (Liverpool) and Canada (Vancouver). The results indicate the presence of an unknown bacterium that shares a homologue for the pla gene of Yersinia pestis, so caution should be taken when using this gene as a diagnostic marker.

Item Type: Article
Keywords: Yersinia pestis, Rodents, Screening, Microarray
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Veterinary Medicine and Science
Identification Number: https://doi.org/10.7717/peerj.2216
Depositing User: Eprints, Support
Date Deposited: 31 Oct 2016 10:52
Last Modified: 01 Nov 2016 17:47
URI: http://eprints.nottingham.ac.uk/id/eprint/38074

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