What have studies of non-industrialized countries told us about the cause of allergic disease?

Fogarty, A.W. (2014) What have studies of non-industrialized countries told us about the cause of allergic disease? Clinical & Experimental Allergy, 45 (1). pp. 87-93. ISSN 1365-2222

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Abstract

The increase in allergic diseases that was observed in countries that had experienced rapid economic growth since the mid-20th century initiated a search for environmental exposures that may explain these phenomena that continues to the present day. Societies that are in the earlier stages of the process of industrialization provide an opportunity to compare the initial stages of economic development and the lifestyle changes that may accompany this, with other communities whose way of life may not have changed appreciably for centuries. These studies have consistently demonstrated higher levels of allergic disease in the relatively affluent populations compared with those who maintain a more traditional lifestyle. Environmental changes that have emerged from these studies that may modify the risk of allergic disease include microbial exposures including parasite infection, pollution, diet and obesity. In addition, food and drug allergies represent a neglected area of research in these countries that may be causing a relatively high burden of disease.

Item Type: Article
Additional Information: This is the peer reviewed version of the following article: A.W. Fogarty, Clinical & Experimental Allergy, 2015 (45) 87–93, which has been published in final form at http://dx.doi.org/10.1111/cea.12339. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Keywords: allergy, asthma, economic development, industrialisation
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Epidemiology and Public Health
Identification Number: https://doi.org/10.1111/cea.12339
Depositing User: Claringburn, Tara
Date Deposited: 24 Oct 2016 07:50
Last Modified: 24 Oct 2016 08:48
URI: http://eprints.nottingham.ac.uk/id/eprint/37795

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