Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK

Nyland, G.A., McKenzie, B.C., Myles, Puja R., Semple, M.G., Lim, W.S., Openshaw, Peter J.M., Read, R.C., Taylor, B.L., Brett, S.J., Mcmenamin, J., Enstone, J.E., Bannister, B., Nicholson, K.G. and Nguyen-Van-Tam, Jonathan (2014) Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK. Epidemiology & Infection, 143 (6). pp. 1129-1138. ISSN 1469-4409

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Data were extracted from the case records of UK patients admitted with laboratory-confirmed influenza A(H1N1)pdm09. White and non-White patients were characterized by age, sex, socioeconomic status, pandemic wave and indicators of pre-morbid health status. Logistic regression examined differences by ethnicity in patient characteristics, care pathway and clinical outcomes; multivariable models controlled for potential confounders. Whites (n = 630) and non-Whites (n = 510) differed by age, socioeconomic status, pandemic wave of admission, pregnancy, recorded obesity, previous and current smoking, and presence of chronic obstructive pulmonary disease. After adjustment for a priori confounders non-Whites were less likely to have received pre-admission antibiotics [adjusted odds ratio (aOR) 0·43, 95% confidence interval (CI) 0·28–0·68, P < 0·001) but more likely to receive antiviral drugs as in-patients (aOR 1·53, 95% CI 1·08–2·18, P = 0·018). However, there were no significant differences by ethnicity in delayed admission, severity at presentation for admission, or likelihood of severe outcome.

Item Type: Article
Keywords: Epidemiology, influenza, influenza A, pandemic
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Epidemiology and Public Health
Identification Number: https://doi.org/10.1017/S0950268814001873
Depositing User: Claringburn, Tara
Date Deposited: 20 Oct 2016 12:17
Last Modified: 08 May 2020 10:15
URI: https://eprints.nottingham.ac.uk/id/eprint/37740

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