Dairy herd mastitis and reproduction: using simulation to aid interpretation of results from discrete time survival analysis

Hudson, Christopher D. and Bradley, Andrew J. and Breen, James E. and Green, Martin J. (2015) Dairy herd mastitis and reproduction: using simulation to aid interpretation of results from discrete time survival analysis. The Veterinary Journal, 204 (1). pp. 47-53. ISSN 1532-2971

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Probabilistic sensitivity analysis (PSA) is a simulation-based technique for evaluating the relative importance of different inputs to a complex process model. It is commonly employed in decision analysis and for evaluation of the potential impact of uncertainty in research findings on clinical practice, but has a wide variety of other possible applications. In this example, it was used to evaluate the association between herd-level udder health and reproductive performance in dairy herds.

Although several recent studies have found relatively large associations between mastitis and fertility at the level of individual inseminations or lactations, the current study demonstrated that herd-level intramammary infection status is highly unlikely to have a clinically significant impact on the overall reproductive performance of a dairy herd under typical conditions. For example, a large increase in incidence rate of clinical mastitis (from 92 to 131 cases per 100 cows per year) would be expected to increase a herd's modified FERTEX score (a cost-based measure of overall reproductive performance) by just £4.501 per cow per year. The herd's background level of submission rate (proportion of eligible cows served every 21 days) and pregnancy risk (proportion of inseminations leading to a pregnancy) correlated strongly with overall reproductive performance and explained a large proportion of the between-herd variation in performance.

PSA proved to be a highly useful technique to aid understanding of results from a complex statistical model, and has great potential for a wide variety of applications within the field of veterinary science.

Item Type: Article
RIS ID: https://nottingham-repository.worktribe.com/output/745811
Keywords: Bayesian; Dairy cow; Fertility performance; Mastitis; Probabilistic sensitivity analysis
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Veterinary Medicine and Science
Identification Number: https://doi.org/10.1016/j.tvjl.2015.01.024
Depositing User: Hudson, Christopher
Date Deposited: 08 Sep 2016 09:59
Last Modified: 04 May 2020 17:03
URI: https://eprints.nottingham.ac.uk/id/eprint/36363

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