A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children

Achana, Felix and Sutton, Alex J. and Kendrick, Denise and Hayes, Mike and Jones, David R. and Hubbard, Stephanie J. and Cooper, Nicola J. (2016) A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children. BMC Public Health, 16 . 705/1-705/17. ISSN 1471-2458

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Background: Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-effectiveness of home safety interventions to promote poison prevention practices.

Methods: A probabilistic decision-analytic model simulates healthcare costs and benefits for a hypothetical cohort of under 5 year olds. The model compares the cost-effectiveness of home safety education, home safety inspections, provision of free or low cost safety equipment and fitting of equipment. Analyses are conducted from a UK National Health Service and Personal Social Services perspective and expressed in 2012 prices.

Results: Education without safety inspection, provision or fitting of equipment was the most cost-effective strategy for promoting safe storage of medicines with an incremental cost-effectiveness ratio of £2888 (95 % credible interval (CrI) £1990–£5774) per poison case avoided or £41,330 (95%CrI £20,007–£91,534) per QALY gained compared with usual care. Compared to usual care, home safety interventions were not cost-effective in promoting safe storage of other household products.

Conclusion: Education offers better value for money than more intensive but expensive strategies for preventing medicinal poisonings, but is only likely to be cost-effective at £30,000 per QALY gained for families in disadvantaged areas and for those with more than one child. There was considerable uncertainty in cost-effectiveness estimates due to paucity of evidence on model parameters. Policy makers should consider both costs and effectiveness of competing interventions to ensure efficient use of resources.

Item Type: Article
Keywords: Economic evaluation; Public health; Injury prevention; Poisonings; Children; Decision models
Schools/Departments: University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Medicine > Division of Primary Care
Identification Number: https://doi.org/10.1186/s12889-016-3334-0
Related URLs:
Depositing User: McCambridge, Mrs April
Date Deposited: 24 Aug 2016 07:32
Last Modified: 13 Sep 2016 14:16
URI: http://eprints.nottingham.ac.uk/id/eprint/35990

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