Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study

Tyrrell, Edward G. and Orton, Elizabeth and Sayal, Kapil and Baker, Ruth and Kendrick, Denise (2016) Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study. Journal of Public Health . ISSN 1741-3850

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Abstract

Background Accurate and up to date data on changes in poisoning incidence among young people are lacking. Recent linkage of UK primary care, hospital and mortality data allows these to be quantified to inform service delivery.

Methods An open cohort study of 1 736 527 young people aged 10–24 between 1998 and 2014 was conducted using linked data from the Clinical Practice Research Datalink, Hospital Episode Statistics and Office for National Statistics deaths. Incidence rates (IRs) by poisoning intent were calculated by age, sex, deprivation and year.

Results Total poisoning IRs increased by 25% from 1998/99 to 2013/14 [adjusted incidence rate ratio (aIRR) 1.25, 95% CI: 1.20–1.30]. Patterns differed markedly by intent. Intentional poisoning rates increased by 52% while unintentional rates remained unchanged. Intentional rates increased almost exclusively among females, gradually between 1998/99 and 2013/14 among 16–18 (88% increase) and 19–24 (36% increase) year olds but only increased among 10–15 year olds in the last 2 years (79% increase). A 2-fold increased risk of poisoning for the most compared to least deprived quintile existed (aIRR 2.21, 95% CI: 2.02–2.23) and remained over time.

Conclusions Commissioning of primary and secondary prevention services needs to address the growing problem of intentional poisonings among young people.

Item Type: Article
Additional Information: This is a pre-copyedited, author-produced PDF of an article accepted for publication in the Journal of Public Health following peer review. The version of record for Tyrrell E.G., Orton E., Sayal K., Baker R., Kendrick, D. Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study. Journal of Public Health 2016; First published online: 13 August 2016:doi:10.1093/pubmed/fdw075 is available online at: http://jpubhealth.oxfordjournals.org/content/early/2016/08/12/pubmed.fdw075.abstract?keytype=ref&ijkey=lo2ojZMSG6kCPxv
Keywords: epidemiology; mental health; young people
Schools/Departments: University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Medicine > Division of Psychiatry
University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Medicine > Division of Primary Care
Identification Number: https://doi.org/10.1093/pubmed/fdw075
Depositing User: McCambridge, Mrs April
Date Deposited: 23 Aug 2016 09:38
Last Modified: 22 Sep 2016 17:49
URI: http://eprints.nottingham.ac.uk/id/eprint/35621

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