Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India

Ahankari, Anand S. and Dixit, J.V. and Fogarty, Andrew W. and Tata, Laila J. and Myles, Puja R. (2016) Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India. BMJ Innovations . ISSN 2055-642X (In Press)

[img] PDF - Repository staff only - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Download (388kB)

Abstract

Objective: The study objective was to compare haemoglobin measurements between the NBM 200 (non-invasive haemoglobin sensor) and Sahli’s hemometer in adolescent girls in a rural Indian setting.

Methods: Participants included girls aged between 13 to 17 years from 34 villages in Tuljapur and Lohara blocks of Osmanabad district, Maharashtra, India. Haemoglobin (Hb) measurements from the non-invasive sensor (NBM 200) were compared with measurements obtained from Sahli’s hemometer using Bland-Altman plot, Spearman correlation coefficient, sensitivity, specificity, and area under the receiver operating characteristic curve analysis (AUROC).

Results: Paired measurements from both methods were obtained from 766 adolescent girls (N=766). Haemoglobin levels estimated by Sahli’s hemometer ranged from 5.0 g/dL to 14.0 g/dL (mean: 10.1 g/dL, standard deviation (SD): 1.41), whereas measurements obtained from the NBM 200 ranged from 9.5 g/dL to 15.2 g/dL (mean: 12.8 g/dL, SD: 1.42). The Bland-Altman analysis indicated a mean difference of -2.70 g/dL (95% Confidence Intervals: -2.84 to -2.55) demonstrating an overestimation of Hb measurement by the NBM 200 compared to the Sahli’s hemometer measurements. The NBM 200 showed low sensitivity (23.6%) and moderate specificity (61.8%) for the diagnosis of anaemia. The AUROC score was 0.43 indicating an underestimation of anaemia in our study population by the NBM 200.

Conclusion: Haemoglobin measurements obtained from the NBM 200 were consistently higher leading to an underestimation of anaemia prevalence compared with Sahli’s hemometer estimates among adolescent girls in India.

Item Type: Article
Keywords: Adolescent, Sahli’s hemometer, Anaemia, Non-invasive Haemoglobin, NBM 200, India
Schools/Departments: University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Medicine > Division of Epidemiology and Public Health
Depositing User: Claringburn, Tara
Date Deposited: 01 Aug 2016 13:30
Last Modified: 26 Sep 2016 15:31
URI: http://eprints.nottingham.ac.uk/id/eprint/35528

Actions (Archive Staff Only)

Edit View Edit View