A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine

Barthelme, Alexandre and Richards, David and Mellor, Ian R. and Stockman, Robert A. (2013) A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine. Chemical Communications, 49 (89). pp. 10507-10509. ISSN 1364-548X

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Abstract

Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.

Item Type: Article
Schools/Departments: University of Nottingham UK Campus > Faculty of Science > School of Chemistry
University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Life Sciences
Identification Number: https://doi.org/10.1039/c3cc46800c
Depositing User: Mellor, Ian
Date Deposited: 25 Jul 2016 08:12
Last Modified: 17 Sep 2016 17:51
URI: http://eprints.nottingham.ac.uk/id/eprint/35316

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