A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine

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Barthelme, Alexandre, Richards, David, Mellor, Ian R. and Stockman, Robert A. (2013) A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine. Chemical Communications, 49 (89). pp. 10507-10509. ISSN 1364-548X

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Official URL: http://pubs.rsc.org/en/Content/ArticleLanding/2013/CC/c3cc46800c#!divAbstract

Abstract

Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.

Item Type:	Article
Schools/Departments:	University of Nottingham, UK > Faculty of Science > School of Chemistry University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Life Sciences
Identification Number:	https://doi.org/10.1039/c3cc46800c
Depositing User:	Mellor, Ian
Date Deposited:	25 Jul 2016 08:12
Last Modified:	13 Oct 2017 16:57
URI:	https://eprints.nottingham.ac.uk/id/eprint/35316

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