Genome-wide analysis reveals the extent of EAV-HP integration in domestic chicken
Wragg, David and Mason, Andrew S. and Yu, Le and Kuo, Richard and Lawal, Raman A. and Desta, Takele Taye and Mwacharo, Joram M. and Cho, Chang-Yeon and Kemp, Steve and Burt, David W. and Hanotte, Olivier (2015) Genome-wide analysis reveals the extent of EAV-HP integration in domestic chicken. BMC Genomics, 16 . 784/1-784/10. ISSN 1471-2164
Background: EAV-HP is an ancient retrovirus pre-dating Gallus speciation, which continues to circulate in modern chicken populations, and led to the emergence of avian leukosis virus subgroup J causing significant economic losses to the poultry industry. We mapped EAV-HP integration sites in Ethiopian village chickens, a Silkie, Taiwan Country chicken, red junglefowl Gallusgallus and several inbred experimental lines using whole-genome sequence data.
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