Psychological interventions for adults with bipolar disorder: a systematic review and meta-analysis

Oud, Matthijs and Mayo-Wilson, Evan and Braidwood, Ruth and Schulte, Peter and Jones, Steven H. and Morriss, Richard K. and Kupka, Ralph and Cuijpers, Pim and Kendall, Tim (2016) Psychological interventions for adults with bipolar disorder: a systematic review and meta-analysis. British Journal of Psychiatry, 208 (3). pp. 213-222. ISSN 1472-1465

[img] PDF - Repository staff only until March 2017. - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Download (1MB)


Background Psychological interventions may be beneficial for bipolar disorder.

Aims Efficacy evaluation of psychological interventions for adults with bipolar disorder.

Methods A systematic review of randomised controlled trials.. Outcomes were meta-analysed using RevMan and confidence assessed using the GRADE-method.

Results We included 55 trials with 6010 participants. Moderate quality evidence associated individual psychological interventions with reduced relapses at post-treatment and follow-up, and collaborative care with a reduction in hospitalisations. . Low quality evidence associated group interventions with fewer depression relapses at post-treatment and follow-up, and family psycho-education with reduced symptoms of depression and mania at post-treatment.

Conclusions There is evidence that psychological interventions are effective for people with bipolar disorder. Limits were the very low quality of much of the evidence and therefore inconclusive. Further research should identify the most (cost)-effective interventions for each phase of this disorder.

Item Type: Article
Additional Information: This is an author-produced electronic version of an article accepted for publication in the British Journal of Psychiatry. The definitive publisher-authenticated version is available online at
Schools/Departments: University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Medicine > Division of Psychiatry
Identification Number:
Depositing User: Eprints, Support
Date Deposited: 24 Mar 2016 14:53
Last Modified: 13 Sep 2016 15:57

Actions (Archive Staff Only)

Edit View Edit View