A probabilistic model for the evaluation of module extraction algorithms in complex biological networks
Gilbert, J.P. (2015) A probabilistic model for the evaluation of module extraction algorithms in complex biological networks. PhD thesis, University of Nottingham.
This thesis presents CiGRAM, a model of complex networks ith known modular structure that is capable of generating realistic graph topology. Much of the recent focus on module detection has been geared towards developing new algorithms capable of detecting biologically significant clusters. However, evaluating clusterings detected by different methods shows that there is little topological agreement or consensus in terms of meta-data despite most methods discovering modules with significant ontology.
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