Enhanced saccadic control in young people with Tourette syndrome despite slowed pro-saccades

Jung, JeYoung and Jackson, Stephen R. and Nam, Kichun and Hollis, Chris and Jackson, Georgina M. (2015) Enhanced saccadic control in young people with Tourette syndrome despite slowed pro-saccades. Journal of Neuropsychology, 9 (2). pp. 172-183. ISSN 1748-6653

[img]
Preview
PDF - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Download (528kB) | Preview

Abstract

Tourette syndrome (TS) is a neurodevelopmental disorder characterised by motor and vocal tics. Tics are repetitive and uncontrolled behaviours that have been associated with basal ganglia dysfunction. We investigated saccadic eye movements in a group of young people with TS but without co-morbid ADHD. Participants performed two tasks. One required them to perform only pro-saccade responses (pure pro-saccade task). The other involved shifting, unpredictably, between executing pro- and anti-saccades (mixed saccade task). We show that in the mixing saccade task, the TS group make significantly fewer errors than an age-matched control group, while responding equally fast. By contrast, on the pure pro-saccade task the TS group were shown to be significantly slower to initiate and to complete the saccades (longer movement duration and decreased peak velocity) than controls, while movement amplitude and direction accuracy were not different. These findings demonstrate enhanced shifting ability despite slower reflexive responding in TS and are discussed with respect to a disorder-related adaptation for increased cognitive regulation of behaviour.

Item Type: Article
Additional Information: This is the peer reviewed version of the following article: Jung, J., Jackson, S. R., Nam, K., Hollis, C. and Jackson, G. M. (2015), Enhanced saccadic control in young people with Tourette syndrome despite slowed pro-saccades. Journal of Neuropsychology, 9: 172–183, which has been published in final form at doi: 10.1111/jnp.12044. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Keywords: Tourette syndrome; cognitive control; task-switching; saccades; eye movements; executive function.
Schools/Departments: University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Medicine > Division of Psychiatry
University of Nottingham UK Campus > Faculty of Science > School of Psychology
Identification Number: https://doi.org/10.1111/jnp.12044
Depositing User: Gohil, Rita
Date Deposited: 20 Oct 2015 12:58
Last Modified: 25 Sep 2016 22:29
URI: http://eprints.nottingham.ac.uk/id/eprint/30488

Actions (Archive Staff Only)

Edit View Edit View