Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species
Giles, Timothy Andrew (2015) Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species. PhD thesis, University of Nottingham.
Emerging infectious diseases are, and have always been, an important threat to human health, animal health and the global economy. Emerging and re-emerging pathogens are opportunists, responding to changes in the host or environment. Therefore, diagnostic tests used for the detection of pathogens either of animal or human origin, must be just as adaptable in utilising new technology. In complex biological situations where multiple pathogens may be present or when using wildlife samples that may be rare or precious, DNA microarray technology is particularly valuable as hundreds or thousands of targets can be screened simultaneously in a single sample.
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