MRS studies of the effects of dietary interventions on hepatic metabolism

Bawden, Stephen (2014) MRS studies of the effects of dietary interventions on hepatic metabolism. PhD thesis, University of Nottingham.

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Abstract

Magnetic Resonance Spectroscopy is a powerful non-invasive tool for investigating liver metabolism in vivo. PRESS and STEAM localized 1H MRS can be used to provide liver lipid measurements calculated from the fat to water peak ratios. Surface coils can also be used to measure other metabolites using multinuclear MRS, 13C MRS directly measures glycogen levels and 31PMRS measures ATP and other phosphate metabolites. This thesis reports on studies undertaken to develop these techniques and describes a number of in vivo investigations that explored the effects of dietary interventions on hepatic metabolism.

Item Type: Thesis (University of Nottingham only) (PhD)
Supervisors: Gowland, Penny
Marciani, Luca
Morris, Peter
Subjects: Q Science > QC Physics > QC501 Electricity and magnetism
Q Science > QP Physiology > QP1 Physiology (General) including influence of the environment
Faculties/Schools: UK Campuses > Faculty of Science > School of Physics and Astronomy
Item ID: 30390
Depositing User: Bawden, Stephen
Date Deposited: 17 Mar 2017 10:00
Last Modified: 23 Sep 2017 18:57
URI: http://eprints.nottingham.ac.uk/id/eprint/30390

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