Electronic communication of cells with a surface mediated by boronic acid saccharide interactions
Stephenson-Brown, Alex and Yong, Sue and Mansor, Muhammad H. and Hussein, Zarrar and Yip, Nga-Chi and Mendes, Paula M. and Fossey, John S. and Rawson, Frankie J. (2015) Electronic communication of cells with a surface mediated by boronic acid saccharide interactions. Chemical Communications, 51 (97). pp. 17181-17330. ISSN 1364-548X
The fabrication of a molecularly tailored surface functionalised with a saccharide binding motif, a phenyl boronic acid derivative is reported.The functionalised surface facilitated the transfer of electrons, via unique electronic interactions mediated by the presence of the boronic acid, from a macrophage cell line. This is the first example of eukaryotic cellular-electrical communication mediated by the binding of cells via their cell–surface saccharide units.
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