Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial

Martin, Kristy-Jane, Lincoln, Nadina and das Nair, Roshan (2014) Group-based memory rehabilitation for people with multiple sclerosis: subgroup analysis of the ReMiND trial. International Journal of Therapy and Rehabilitation, 21 (12). pp. 422-428. ISSN 1741-1645

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Background/Aim: Memory problems are frequently reported in people with multiple sclerosis (MS). These can be debilitating and affect individuals and their families. This sub-group analysis focused on the effectiveness of memory rehabilitation in patients with MS.

Methods: Data were extracted from a single blind randomised controlled trial, the ReMiND trial, which also included participants with traumatic brain injury and stroke. Participants were randomly allocated to compensation or restitution treatment programmes, or a self-help control. The programmes were manual-based and comprised two individual and ten group sessions. Outcome measures included assessments of memory, mood and activities of daily living. A total of 39 patients with MS participated in this study (ten males (26%), 29 females (74%); mean±SD age: 48.3±10.8 years). Results: Comparison of groups showed no significant effect of treatment on memory, but there were significant differences between compensation and restitution on self-report symptoms of emotional distress at both 5- (p=0.04) and 7-month (p=0.05) follow-up sessions. The compensation group showed less distress than the restitution group.

Conclusions: Individuals with MS who received compensation memory rehabilitation reported significantly less emotional distress than those who received restitution. Further research is needed to explore why self-reported memory problems did not differ between groups.

Item Type: Article
Keywords: Multiple sclerosis, Memory, Rehabilitation, Randomised controlled trial
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Rehabilitation and Ageing
Identification Number:
Depositing User: Martin, Kristy-jane
Date Deposited: 11 Jun 2015 13:56
Last Modified: 04 May 2020 16:59

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