Three dimensional cell reconstructions for morphological analysis and modelling
Ratcliffe, Jonathan Albert (2011) Three dimensional cell reconstructions for morphological analysis and modelling. PhD thesis, University of Nottingham.
It is highly desirable to devise a systematic approach to predict cell – material interactions, especially for novel biomaterial surfaces, and to further understanding in the complex area of attachment and spreading. The aim of this research was to produce a new method of studying morphology in real time, whereby data from live spreading cells can be collected for mathematical modelling. There is an abundance of models for sub-cellular elements, however, there are few calibrated models of whole cells; in particular, three-dimensional models predicting attachment, spreading and cell morphology have yet to be produced.
Actions (Archive Staff Only)