Skeletal muscle carnitine metabolism during intense exercise in human volunteers
Shannon, C.E. (2016) Skeletal muscle carnitine metabolism during intense exercise in human volunteers. PhD thesis, University of Nottingham.
Increasing skeletal muscle carnitine content enhances PDC flux during 30 minutes of continuous exercise at 80% Wmax, reducing reliance on non-mitochondrial ATP production and improving work output. These studies in healthy volunteers evaluated a carnitine feeding strategy that did not rely on the high carbohydrate load previously used, then investigated whether manipulating muscle carnitine could alter the adaptations to a period of submaximal high-intensity intermittent training (HIT).
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