Alkaloid inspired spirocyclic oxindoles from 1,3-dipolar cycloaddition of pyridinium ylides

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Day, Jonathan, Uroos, Maliha, Castledine, Richard A., Lewis, William, McKeever-Abbas, Ben and Dowden, James (2013) Alkaloid inspired spirocyclic oxindoles from 1,3-dipolar cycloaddition of pyridinium ylides. Organic and Biomolecular Chemistry, 11 (38). pp. 6502-6509. ISSN 1477-0520

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Official URL: http://pubs.rsc.org/en/content/articlelanding/2013/ob/c3ob41415a#!divAbstract

Abstract

Cycloaddition reactions between pyridinium ylides and 3-alkenyl oxindoles that proceed in high yield and with very good regio- and diastereoselectivity are reported. The resulting cycloadducts have the same stereochemistry of biologically active oxindole alkaloids, such as strychnofoline.

Item Type:	Article
RIS ID:	https://nottingham-repository.worktribe.com/output/717062
Schools/Departments:	University of Nottingham, UK > Faculty of Science > School of Chemistry
Identification Number:	https://doi.org/10.1039/C3OB41415A
Depositing User:	Snowden, Ms Diane
Date Deposited:	01 Apr 2014 14:17
Last Modified:	04 May 2020 16:38
URI:	https://eprints.nottingham.ac.uk/id/eprint/2738

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