Intersection of inflammation and herbal medicine in the treatment of osteoarthritis

Mobasheri, Ali (2012) Intersection of inflammation and herbal medicine in the treatment of osteoarthritis. Current Rheumatology Reports, 14 (6). pp. 604-616. ISSN 1523-3774

[img] PDF - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Available under Licence Creative Commons Attribution.
Download (350kB)

Abstract

Herbal remedies and dietary supplements have become an important area of research and clinical practice in orthopaedics and rheumatology. Understanding the risks and benefits of using herbal medicines in the treatment of arthritis, rheumatic diseases, and musculoskeletal complaints is a key priority of physicians and their patients. This review discusses the latest advances in the use of herbal medicines for treating osteoarthritis (OA) by focusing on the most significant trends and developments. This paper sets the scene by providing a brief introduction to ethnopharmacology, Ayurvedic medicine, and nutrigenomics before discussing the scientific and mechanistic rationale for targeting inflammatory signalling pathways in OA by use of herbal medicines. Special attention is drawn to the conceptual and practical difficulties associated with translating data from in-vitro experiments to in-vivo studies. Issues relating to the low bioavailability of active ingredients in herbal medicines are discussed, as also is the need for large-scale, randomized clinical trials

Item Type: Article
Schools/Departments: University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Veterinary Medicine and Science
Identification Number: https://doi.org/10.1007/s11926-012-0288-9
Depositing User: Johnson, Mrs Alison
Date Deposited: 27 Mar 2014 12:31
Last Modified: 14 Sep 2016 03:25
URI: http://eprints.nottingham.ac.uk/id/eprint/2706

Actions (Archive Staff Only)

Edit View Edit View