Characterisation of a group of endogenous gammaretroviruses in the canine genome

Tarlinton, Rachael E. and Barfoot, Hannah K.R. and Allen, Ceri E. and Brown, Katherine and Gifford, Robert J. and Emes, Richard D. (2013) Characterisation of a group of endogenous gammaretroviruses in the canine genome. Veterinary Journal, 196 (1). pp. 28-33. ISSN 1090-0233

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Abstract

Bioinformatics were used to identify and characterise 39 pol, 34 gag and five env gammaretroviruses within the canine (Canis lupus familiaris) reference genome. These endogenous retroviruses are monophyletic to the Canidae, predate the divergence of dogs and foxes and are fixed in 20 canine breeds examined. They are transcribed in normal canine tissue but are unlikely to be replication competent in dogs.

Item Type: Article
Keywords: Canine, Endogenous retroviruses, Gammaretroviruses
Schools/Departments: University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Veterinary Medicine and Science
Depositing User: Davies, Mrs Sarah
Date Deposited: 23 Apr 2014 11:54
Last Modified: 13 Sep 2016 11:55
URI: http://eprints.nottingham.ac.uk/id/eprint/2476

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