Modelling FTIR spectral sata with Type-I and Type-II fuzzy sets for breast cancer grading
Naqvi, Shabbar (2014) Modelling FTIR spectral sata with Type-I and Type-II fuzzy sets for breast cancer grading. PhD thesis, University of Nottingham.
Breast cancer is one of the most frequently occurring cancers amongst women throughout the world. After the diagnosis of the disease, monitoring its progression is important in predicting the chances of long term survival of patients. The Nottingham Prognostic Index (NPI) is one of the most common indices used to categorise the patients into different groups depending upon the severity of the disease. One of the key factors of this index is cancer grade which is determined by pathologists who examine cell samples under a microscope. This manual method has a higher chance of false classification and may lead to incorrect treatment of patients. There is a need to develop automated methods that employ advanced computational methods to help pathologists in making a decision regarding the classification of breast cancer grade. Fourier transform infra-red spectroscopy (FTIR) is one of the relatively new techniques that has been used for diagnosis of various cancer types with advanced computational methods in the literature. In this thesis we examine the use of advanced fuzzy methods with the FTIR spectral data sets to develop a model prototype that can help clinicians with breast cancer grading.
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