Development of rapid phage based detection methods for mycobacteria
Swift, Benjamin M.C. (2014) Development of rapid phage based detection methods for mycobacteria. PhD thesis, University of Nottingham.
MAP is the causative agent of a wasting disease in ruminants and other animals called Johne’s disease. Culture of the organism can take months and in the case of some sheep strains of MAP, culture can take up to a year. It can take several years for an animal infected with MAP to show clinical symptoms of disease. During this subclinical stage of infection, MAP can be shed into the environment contaminating their surroundings and infecting other animals. As well as this Johne’s disease is particularly difficult to diagnose during the subclinical stage of infection.
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