A multiscale analysis of flow and transport in the human placenta
Chernyavsky, Igor L. (2011) A multiscale analysis of flow and transport in the human placenta. PhD thesis, University of Nottingham.
The human placenta is characterised by a unique circulatory arrangement, with numerous villous trees containing fetal vessels immersed in maternal blood. Placental tissue therefore manifests a multiscale structure balancing microscopic delivery of nutrients and macroscopic flow. The aims of this study are to examine the interaction between these scales and to understand the influence of placental organisation on the effectiveness of nutrient uptake, which can be compromised in pathologies like pre-eclampsia and diabetes.
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