Nutritional targeting of inflammatory pathways and catabolic mediators involved in equine osteoarthritis
Clutterbuck, A. (2011) Nutritional targeting of inflammatory pathways and catabolic mediators involved in equine osteoarthritis. PhD thesis, University of Nottingham.
Osteoarthritis (OA) is a degenerative disease of synovial joints with an inflammatory component, which affects humans and companion animals, including horses. Current pharmacotherapy for OA is associated with deleterious side effects. Therefore, plant-derived products with anti-inflammatory properties may provide safer natural alternatives. The project aimed to use in vitro models of equine cartilage to test the hypothesis that plant-derived extracts would reduce inflammation and degradation in an explant model of early OA.
Actions (Archive Staff Only)