Evolution of CCL3L1/CCL4L1 haplotypes
Janyakhantikul, Somwang (2011) Evolution of CCL3L1/CCL4L1 haplotypes. PhD thesis, University of Nottingham.
CCL3LI and CCL4LI are chemokine genes, located on chromosome 17q12. They are copy number variable genes which share 95% sequence identity with their non-copy number variable paralogues CCL3 and CCL4. The copy number of these genes varies between populations and has been reported to be associated with phenotypes such as susceptibility to HIV infection, hepatitis C virus infection, Kawasaki disease and SLE.
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