Statistical inference and modelling for nosocomial infections and the incorporation of whole genome sequence data
Worby, Colin J. (2013) Statistical inference and modelling for nosocomial infections and the incorporation of whole genome sequence data. PhD thesis, University of Nottingham.
Healthcare-associated infections (HCAIs) remain a problem worldwide, and can cause severe illness and death. The increasing level of antibiotic resistance among bacteria that cause HCAIs limits infection treatment options, and is a major concern. Statistical modelling is a vital tool in developing an understanding of HCAI transmission dynamics. In this thesis, stochastic epidemic models are developed and used with the aim of investigating methicillin-resistant Staphylococcus aureus (MRSA) transmission and intervention measures in hospital wards.
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