Investigation into the ion channels and plasma membrane properties of white adipocytes
Bentley, Donna C. (2013) Investigation into the ion channels and plasma membrane properties of white adipocytes. PhD thesis, University of Nottingham.
Ca2+ is a ubiquitous intracellular signalling molecule that is involved in the regulation of numerous cellular functions. To date Ca2+ influx pathways present in white fat adipocytes have not been characterised. Additionally impaired [Ca2+]i management is implicated in the induction of the insulin resistant state in adipocytes. As adipocytes have a prominent role in the management of energy homeostasis, the presence of Ca2+ influx pathways was examined.
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