The definition of Echinococcus multilocularis differentially expressed molecules using deep sequencing
Zheng, Yadong (2012) The definition of Echinococcus multilocularis differentially expressed molecules using deep sequencing. PhD thesis, University of Nottingham.
Echinococcus multilocularis has recently been developed as a model for basic and applied studies on trematodes and cestodes. Deep understanding of molecular biology of this parasite is urgently required for efficient and extensive applications such as functional gene probing and anti-helminth drug screening. In our project, we aimed to unveil E. multilocularis miRNA repertoires and the identification of differentially expressed molecules from the mRNA and miRNA transcriptomes using next-generation sequencing technology. Furthermore, one family of E. multilocularis molecules identified, fatty acid-binding proteins that are involved in lipid metabolisms, was phylogenetically and functionally characterized.
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