Perinatal programming of appetite regulation and metabolic health
Dellschaft, Neele S. (2012) Perinatal programming of appetite regulation and metabolic health. PhD thesis, University of Nottingham.
According to the concept of perinatal programming environmental factors during fetal development and early postnatal life can influence phenotype in later life by modifying organ and tissue development and the epigenetic information of specific genes which, in turn, induce alteration in gene expression. Global nutrient restriction is a well-established intervention to study fetal programming but choline, a micronutrient essential for tissue growth and development, has not been extensively studied.
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