The effects of a high molecular weight glucose polymer on muscle metabolism and exercise performance in humans
Gunner, Frances (2012) The effects of a high molecular weight glucose polymer on muscle metabolism and exercise performance in humans. PhD thesis, University of Nottingham.
The work in this thesis has investigated the potential for a unique HMW glucose polymer (Vitargo, Swecarb AB, Sweden; MW of 500-700 g.mol-1) derived from barley starch to augment short-term post exercise muscle glycogen resynthesis above that of an isoenergetic LMW glucose polymer (Maxijul, SHS International, UK; MW of 900 g.mol-1). The HMW glucose polymer has been previously investigated in comparison to a LMW glucose solution with studies reporting a 70% greater muscle glycogen content after 2 hr recovery from glycogen-depleting exercise (Piehl-Aulin et al., 2000) and an enhanced gastric emptying at rest (Leiper et al., 2000). More recently an improved work output (10%) in a maximal exercise test performed 2 hr after exhaustive exercise was demonstrated after ingestion of the HMW glucose polymer compared to an isoenergetic LMW glucose polymer (Stephens et al., 2008). Key observations in this study were a greater rate of rise in blood glucose and serum insulin concentration during recovery with ingestion of the HMW compared to the LMW glucose polymer. Thus it was suggested that the improvement in performance in the secondary exercise bout could potentially be attributed to greater muscle glycogen availability present at the onset of the test.
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