Intra-articular depot forming drug delivery system for osteoarthritis
Freddi, Matthew James (2012) Intra-articular depot forming drug delivery system for osteoarthritis. PhD thesis, University of Nottingham.
Osteoarthritis (OA) is a chronic degenerative disease of the joint. Current treatments for this disease (such as glucocorticoid steroids) aim to reduce pain and increase mobility. Intra-articular injection is used in OA as treatment can be targeted to affected joints only. There is currently a lack of sustained release formulations for intra-articular injection.
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