Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer

Rampaul, R.S. and Miremadi, A. and Pinder, S.E. and Lee, A. and Ellis, I.O. (2001) Pathological validation and significance of micrometastasis in sentinel nodes in primary breast cancer. Breast Cancer Research, 3 (2). pp. 113-116.

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Abstract

In embracing a multidisciplinary approach to the management of patients with sentinel node biopsy in breast cancer, the pathologist task is to screen sentinel nodes for possible metastasis. The consequences of missing sentinel node micrometastasis can directly influence treatment strategies, and this screening therefore has to be performed with more attention than usual. There is presently great diversity in the histopathological work-up of sentinel nodes, with many centres employing additional techniques such as immunohistochemistry, reverse transcription polymerase chain reaction or flow cytometry in addition to routine haematoxylin and eosin staining. In this review, we address the pathological validation and significance of micrometastasis in sentinel node biopsy in primary breast cancer

Item Type: Article
Schools/Departments: University of Nottingham UK Campus > Faculty of Medicine and Health Sciences > School of Life Sciences > School of Molecular Medical Sciences > Cancer
Depositing User: Gardner, Mike
Date Deposited: 30 Jul 2004
Last Modified: 13 Aug 2013 10:26
URI: http://eprints.nottingham.ac.uk/id/eprint/125

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