Characterisation of anti-glycan monoclonal antibodies
Noble, Philip W. (2011) Characterisation of anti-glycan monoclonal antibodies. PhD thesis, University of Nottingham.
The aims of this thesis are to establish the therapeutic value of two anti-glycan mAbs produced in-house, to develop an immunisation protocol with the aim of improving the immunogenicity tumour-associated glycolipids with the intention of producing therapeutically valuable mAbs and to determine the implication of a mAb with the ability to induce apoptosis in colorectal cancer.
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