Polymer bioadhesives for drug delivery
Deacon, Matthew (1999) Polymer bioadhesives for drug delivery. PhD thesis, University of Nottingham.
This study is a natural follow on from previous work by M. T. Anderson and I. Fiebrig. The goal of those latter and of the present study is to find a mucoadhesive system for improving the oral bioavailability of a number of drugs, for example bioactive peptides and proteins. This current work evaluates the adhesive properties of a cationic polymer and a cationic protein to mucus glycoproteins as a step towards the future development of a mucoadhesive drug delivery system.
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